Pesquisa | Secretaria de Estado da Saúde

1.

Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation.

Federici, Sara; Kredo-Russo, Sharon; Valdés-Mas, Rafael; Kviatcovsky, Denise; Weinstock, Eyal; Matiuhin, Yulia; Silberberg, Yael; Atarashi, Koji; Furuichi, Munehiro; Oka, Akihiko; Liu, Bo; Fibelman, Morine; Weiner, Iddo Nadav; Khabra, Efrat; Cullin, Nyssa; Ben-Yishai, Noa; Inbar, Dana; Ben-David, Hava; Nicenboim, Julian; Kowalsman, Noga; Lieb, Wolfgang; Kario, Edith; Cohen, Tal; Geffen, Yael Friedman; Zelcbuch, Lior; Cohen, Ariel; Rappo, Urania; Gahali-Sass, Inbar; Golembo, Myriam; Lev, Vered; Dori-Bachash, Mally; Shapiro, Hagit; Moresi, Claudia; Cuevas-Sierra, Amanda; Mohapatra, Gayatree; Kern, Lara; Zheng, Danping; Nobs, Samuel Philip; Suez, Jotham; Stettner, Noa; Harmelin, Alon; Zak, Naomi; Puttagunta, Sailaja; Bassan, Merav; Honda, Kenya; Sokol, Harry; Bang, Corinna; Franke, Andre; Schramm, Christoph; Maharshak, Nitsan.

Cell ; 185(16): 2879-2898.e24, 2022 08 04.

Artigo Inglês | MEDLINE | ID: mdl-35931020

2.

Biosynthesis and Export of Bacterial Glycolipids.

Caffalette, Christopher A; Kuklewicz, Jeremi; Spellmon, Nicholas; Zimmer, Jochen.

Annu Rev Biochem ; 89: 741-768, 2020 06 20.

Artigo Inglês | MEDLINE | ID: mdl-32569526

3.

Effector T_H17 Cells Give Rise to Long-Lived T_RM Cells that Are Essential for an Immediate Response against Bacterial Infection.

Amezcua Vesely, Maria Carolina; Pallis, Paris; Bielecki, Piotr; Low, Jun Siong; Zhao, Jun; Harman, Christian C D; Kroehling, Lina; Jackson, Ruaidhrí; Bailis, Will; Licona-Limón, Paula; Xu, Hao; Iijima, Norifumi; Pillai, Padmini S; Kaplan, Daniel H; Weaver, Casey T; Kluger, Yuval; Kowalczyk, Monika S; Iwasaki, Akiko; Pereira, Joao P; Esplugues, Enric; Gagliani, Nicola; Flavell, Richard A.

Cell ; 178(5): 1176-1188.e15, 2019 08 22.

Artigo Inglês | MEDLINE | ID: mdl-31442406

4.

Innate Lymphocyte/Ly6C(hi) Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance.

Xiong, Huizhong; Keith, James W; Samilo, Dane W; Carter, Rebecca A; Leiner, Ingrid M; Pamer, Eric G.

Cell ; 165(3): 679-89, 2016 Apr 21.

Artigo Inglês | MEDLINE | ID: mdl-27040495

5.

Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen.

Rollenske, Tim; Szijarto, Valeria; Lukasiewicz, Jolanta; Guachalla, Luis M; Stojkovic, Katarina; Hartl, Katharina; Stulik, Lukas; Kocher, Simone; Lasitschka, Felix; Al-Saeedi, Mohammed; Schröder-Braunstein, Jutta; von Frankenberg, Moritz; Gaebelein, Gereon; Hoffmann, Peter; Klein, Sabrina; Heeg, Klaus; Nagy, Eszter; Nagy, Gabor; Wardemann, Hedda.

Nat Immunol ; 19(6): 617-624, 2018 06.

Artigo Inglês | MEDLINE | ID: mdl-29760533

6.

The global RNA-RNA interactome of Klebsiella pneumoniae unveils a small RNA regulator of cell division.

Ruhland, Eric; Siemers, Malte; Gerst, Ruman; Späth, Felix; Vogt, Laura Nicole; Figge, Marc Thilo; Papenfort, Kai; Fröhlich, Kathrin Sophie.

Proc Natl Acad Sci U S A ; 121(9): e2317322121, 2024 Feb 27.

Artigo Inglês | MEDLINE | ID: mdl-38377209

7.

Tracing My Roots: How I Became a Plant Biologist.

Ausubel, Frederick M.

Annu Rev Genet ; 52: 1-20, 2018 11 23.

Artigo Inglês | MEDLINE | ID: mdl-30192637

8.

In vivo single-cell high-dimensional mass cytometry analysis to track the interactions between Klebsiella pneumoniae and myeloid cells.

Calderon-Gonzalez, Ricardo; Dumigan, Amy; Sá-Pessoa, Joana; Kissenpfennig, Adrien; Bengoechea, José A.

PLoS Pathog ; 20(4): e1011900, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-38578798

9.

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens.

Branzk, Nora; Lubojemska, Aleksandra; Hardison, Sarah E; Wang, Qian; Gutierrez, Maximiliano G; Brown, Gordon D; Papayannopoulos, Venizelos.

Nat Immunol ; 15(11): 1017-25, 2014 Nov.

Artigo Inglês | MEDLINE | ID: mdl-25217981

10.

Klebsiella pneumoniae: adaptive immune landscapes and vaccine horizons.

Wantuch, Paeton L; Rosen, David A.

Trends Immunol ; 44(10): 826-844, 2023 10.

Artigo Inglês | MEDLINE | ID: mdl-37704549

11.

Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site.

Pantel, Lucile; Florin, Tanja; Dobosz-Bartoszek, Malgorzata; Racine, Emilie; Sarciaux, Matthieu; Serri, Marine; Houard, Jessica; Campagne, Jean-Marc; de Figueiredo, Renata Marcia; Midrier, Camille; Gaudriault, Sophie; Givaudan, Alain; Lanois, Anne; Forst, Steve; Aumelas, André; Cotteaux-Lautard, Christelle; Bolla, Jean-Michel; Vingsbo Lundberg, Carina; Huseby, Douglas L; Hughes, Diarmaid; Villain-Guillot, Philippe; Mankin, Alexander S; Polikanov, Yury S; Gualtieri, Maxime.

Mol Cell ; 70(1): 83-94.e7, 2018 04 05.

Artigo Inglês | MEDLINE | ID: mdl-29625040

12.

Identification of a second glycoform of the clinically prevalent O1 antigen from Klebsiella pneumoniae.

Kelly, Steven D; Ovchinnikova, Olga G; Müller, Fabian; Steffen, Michael; Braun, Martin; Sweeney, Ryan P; Kowarik, Michael; Follador, Rainer; Lowary, Todd L; Serventi, Fabio; Whitfield, Chris.

Proc Natl Acad Sci U S A ; 120(29): e2301302120, 2023 07 18.

Artigo Inglês | MEDLINE | ID: mdl-37428935

13.

Antimicrobial resistance heterogeneity among multidrug-resistant Gram-negative pathogens: Phenotypic, genotypic, and proteomic analysis.

Mehrotra, Tanshi; Konar, Dipasri; Pragasam, Agila Kumari; Kumar, Shakti; Jana, Pradipta; Babele, Prabhakar; Paul, Deepjyoti; Purohit, Ayushi; Tanwar, Subhash; Bakshi, Susmita; Das, Santanu; Verma, Jyoti; Talukdar, Daizee; Narendrakumar, Lekshmi; Kothidar, Akanksha; Karmakar, Sonali Porey; Chaudhuri, Susmita; Pal, Sujoy; Jain, Kajal; Srikanth, Chittur V; Sankar, M Jeeva; Atmakuri, Krishnamohan; Agarwal, Ramesh; Gaind, Rajni; Ballal, Mamatha; Kammili, Nagamani; Bhadra, Rupak K; Ramamurthy, Thandavarayan; Nair, G Balakrish; Das, Bhabatosh.

Proc Natl Acad Sci U S A ; 120(33): e2305465120, 2023 08 15.

Artigo Inglês | MEDLINE | ID: mdl-37549252

14.

Antimicrobial resistance level and conjugation permissiveness shape plasmid distribution in clinical enterobacteria.

Alonso-Del Valle, Aida; Toribio-Celestino, Laura; Quirant, Anna; Pi, Carles Tardio; DelaFuente, Javier; Canton, Rafael; Rocha, Eduardo P C; Ubeda, Carles; Peña-Miller, Rafael; San Millan, Alvaro.

Proc Natl Acad Sci U S A ; 120(51): e2314135120, 2023 Dec 19.

Artigo Inglês | MEDLINE | ID: mdl-38096417

15.

Klebicin E, a pore-forming bacteriocin of Klebsiella pneumoniae, exploits the porin OmpC and the Ton system for translocation.

Zhao, Xinxin; Wang, Wenyu; Zeng, Xiaoli; Xu, Rong; Yuan, Bing; Yu, Wenyao; Wang, Mingshu; Jia, Renyong; Chen, Shun; Zhu, Dekang; Liu, Mafeng; Yang, Qiao; Wu, Ying; Zhang, Shaqiu; Huang, Juan; Ou, Xumin; Sun, Di; Cheng, Anchun.

J Biol Chem ; 300(3): 105694, 2024 Mar.

Artigo Inglês | MEDLINE | ID: mdl-38301890

16.

Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.

Sun, Zhizeng; Lin, Hanfeng; Hu, Liya; Neetu, Neetu; Sankaran, Banumathi; Wang, Jin; Prasad, B V Venkataram; Palzkill, Timothy.

J Biol Chem ; 300(1): 105493, 2024 Jan.

Artigo Inglês | MEDLINE | ID: mdl-38000656

17.

A curated collection of Klebsiella metabolic models reveals variable substrate usage and gene essentiality.

Hawkey, Jane; Vezina, Ben; Monk, Jonathan M; Judd, Louise M; Harshegyi, Taylor; López-Fernández, Sebastián; Rodrigues, Carla; Brisse, Sylvain; Holt, Kathryn E; Wyres, Kelly L.

Genome Res ; 32(5): 1004-1014, 2022 05.

Artigo Inglês | MEDLINE | ID: mdl-35277433

18.

RVFScan predicts virulence factor genes and hypervirulence of the clinical metagenome.

Jiang, Yue; Hu, Xuejiao; Fan, Shu; Liu, Weijiang; Chen, Jingjing; Wang, Liang; Deng, Qianyun; Yang, Jing; Yang, Aimei; Lou, Zheng; Guan, Yuanlin; Xia, Han; Gu, Bing.

Brief Bioinform ; 24(6)2023 09 22.

Artigo Inglês | MEDLINE | ID: mdl-37930030

19.

Klebsiella pneumoniae causes bacteremia using factors that mediate tissue-specific fitness and resistance to oxidative stress.

Holmes, Caitlyn L; Wilcox, Alexis E; Forsyth, Valerie; Smith, Sara N; Moricz, Bridget S; Unverdorben, Lavinia V; Mason, Sophia; Wu, Weisheng; Zhao, Lili; Mobley, Harry L T; Bachman, Michael A.

PLoS Pathog ; 19(7): e1011233, 2023 07.

Artigo Inglês | MEDLINE | ID: mdl-37463183

20.

Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae.

Wantuch, Paeton L; Knoot, Cory J; Robinson, Lloyd S; Vinogradov, Evgeny; Scott, Nichollas E; Harding, Christian M; Rosen, David A.

PLoS Pathog ; 19(5): e1011367, 2023 05.

Artigo Inglês | MEDLINE | ID: mdl-37146068

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